680-31-9
- Product Name：Hexamethyl phosphoramide
- Molecular Formula：C6H18N3OP
- Purity：99%
- Molecular Weight：179.20
Product Details
Purity:99%
Hot Sale, We supply Industrial Grade Hexamethyl phosphoramide 680-31-9, in stock.
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680-31-9 Name |
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Name |
Hexamethyl phosphoramide |
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Synonym |
Eastman Inhibitor HPT;eastmaninhibitorhpt;ENT 50,882;ENT 50882;Hexmethylphosphoramide;HMPTA;HPT;Phosphoric acid hexamethyltriamide |
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680-31-9 Chemical & Physical Properties |
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Melting point |
7 °C(lit.) |
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Boiling point |
230-232 °C740 mm Hg(lit.) |
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Density |
1.03 g/mL at 25 °C(lit.) |
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Molecular Formula |
C6H18N3OP |
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Molecular Weight |
179.20000 |
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Form |
Liquid |
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Color |
Colorless to light yellow liquid |
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Flash Point |
222 °F |
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PSA |
36.60000 |
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LogP |
0.77930 |
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Exact Mass |
179.11900 |
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Vapour density |
6.18 (vs air) |
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Vapour Pressure |
0.07 mm Hg ( 25 °C) |
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Index of Refraction |
n20/D 1.459(lit.) |
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Stability |
Stable. Incompatible with strong acids, strong oxidizing agents. |
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Water Solubility |
Miscible |
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Freezing Point |
7°C |
Industrial Grade Hexamethyl phosphoramide 680-31-9
Hexamethylphosphoramide (HMPA) is extensively used in various applications and it is considered a reliable ionizing solvent for superbases. Hexamethylphosphoramide (HMPA), is incorporated as a cosolvent for aqueous electrolyte to stabilize the Zn anode.
Fire Hazard
Hexamethylphosphoramide is combustible.
Waste Disposal
Excess hexamethylphosphoramide and waste material containing this substance should be placed in an appropriate container, clearly labeled, and handled according to your institution's waste disposal guidelines.
InChI:InChI=1/C6H18N3OP/c1-7(2)11(10,8(3)4)9(5)6/h1-6H3
680-31-9 Relevant articles
Development of Ru(bpy)32+ electrochemiluminescence sensor for highly sensitive detection of carcinogenic and mutagenic hexamethylphosphoramide
Tesfaye Hailemariam Barkae, Abdallah M. Zeid, Shuai Quan, Muhammad Rehan Hasan Shah Gilani, Baohua Lou, Guobao Xu
, Journal of Electroanalytical Chemistry Volume 904, 1 January 2022, 115954
The effect of chemosterilant Hexamethylphosphoramide (HEMPA) on developing oocyte follicles in the fruit piercing moth Eudocima materna were studied. In line with the wide and broad application of HMPA, we designed a Ru(bpy)32+ ECL sensor for sensitive and selective detection of a phosphoramide, HMPA, for the first time. Importantly, the developed sensor was utilized for the detection of HMPA in lake water and waste water samples with high %recovery (98.0–102.5%).
Cyclophosphamide, hydroxycyclophosphamide and carboxyethyl phosphoramide mustard quantification with liquid chromatography mass spectrometry in a single run human plasma samples: A rapid and sensitive method development
Kripa Shanker Kasudhan, Ajay Patial, Nancy Mehra, Savita Verma Attri, Pankaj Malhotra, Smita Pattanaik, Deepesh Lad, Amol N. Patil
Journal of Chromatography B Volume 1198, 15 May 2022, 123228
Hexamethylphosphoramide is considered a reliable ionizing solvent for superbases. Semicarbazide was used as a stabilizing agent for HCy whereas ifosfamide, hexamethyl phosphoramide mustard and deuterated CEPM were the internal standards for quantification of Cy, HCy and CEPM respectively.
680-31-9 Process route
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- 85121-05-7
C8H5I*C6H18N3OP
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- 680-31-9
N,N,N,N,N,N-hexamethylphosphoric triamide
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- 506-78-5
cyanogen iodide
| Conditions | Yield |
|---|---|
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In benzene; at 21 ℃; Equilibrium constant;
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C2H5FO*C6H18N3OP
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- 680-31-9
N,N,N,N,N,N-hexamethylphosphoric triamide
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- 371-62-0
2-fluoroethanol
| Conditions | Yield |
|---|---|
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In octanol; at 24.84 ℃; Equilibrium constant;
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