1197-18-8
- Product Name：Tranexamic acid
- Molecular Formula：C8H15NO2
- Purity：99%
- Molecular Weight：157.21
Product Details
Purity:99%
We supply Cosmetics Grade Tranexamic acid 1197-18-8, In Stock.
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1197-18-8 Name |
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Name |
Tranexamic acid |
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Synonym |
TIMTEC-BB SBB006715;TRANS-4-AMINOMETHYL-1-CYCLOHEXANECARBOXYLIC ACID;trans-4-aminomethylcyclohexane-1-carboxylate;TRANS-4-(AMINOMETHYL)CYCLOHEXANECARBOXYLIC ACID;cyclocapron;cyklokapron;dv-79;emorhalt |
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1197-18-8 Biological Activity |
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Related Catalog |
Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease |
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1197-18-8 Chemical & Physical Properties |
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Melting point |
>300 °C(lit.) |
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Boiling point |
300.2±15.0 °C at 760 mmHg |
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Density |
1.1±0.1 g/cm3 |
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Molecular Formula |
C8H15NO2 |
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Molecular Weight |
157.210 |
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Flash Point |
135.4±20.4 °C |
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PSA |
63.32000 |
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LogP |
0.31 |
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Exact Mass |
157.110275 |
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Vapour Pressure |
0.0±1.3 mmHg at 25°C |
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Index of Refraction |
1.497 |
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storage temp. |
2-8°C |
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Water Solubility |
1G/6ML |
Cosmetics Grade Tranexamic acid 1197-18-8
Tranexamic acid (TXA) is an efficient antifibrinolytic agent which is a derivative of aminomethylbenzoic acid, and a kind of antifibrinolytic drugs to stop bleeding. The hemostasis mechanism of tranexamic acid is similar to aminocaproic acid and aminomethylbenzoic acid, but the effect is stronger. The strength is 7 to 10 times of aminocaproic acid, 2 times of aminomethylbenzoic acid, but toxicity is similar. The chemical structure of tranexamic acid is similar to lysine, competitive inhibition of plasmin original in fibrin adsorption, to prevent their activation, protection fiber protein not to degrade by plasmin and dissolve, eventually achieve hemostasis.Tranexamic acid is available in intravenous and oral formulations. It is safe and effective in both medical and surgical patients. In the presence of tranexamic acid, the lysine receptor binding sites of plasmin for fibrin are occupied, preventing binding to fibrin monomers, thus preserving and stabilizing fibrin’s matrix structure.
InChI:InChI=1/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
1197-18-8 Relevant articles
In reply: Accidental infusion of tranexamic acid via a thoracic epidural catheter
CL Pysyk, L Filteau
Canadian Journal of Anesthesia/Journal canadien d'anesthésie (2023)
Patel for his interest in our case report of a patient with accidental administration of tranexamic acid (TXA) into the epidural space.
Tranexamic acid is not associated with decreased infection risk after primary shoulder arthroplasty: a cohort study of 9276 patients
Jacob Gorbaty MD , Priscilla H. Chan MS , Matthew D. McElvany MD , Heather A. Prentice PhD , Edward H. Yian MD
Journal of Shoulder and Elbow Surgery Volume 32, Issue 3, March 2023, Pages 581-588
The use of tranexamic acid (TXA) is associated with less blood loss and reduced transfusion risk after shoulder arthroplasty surgery. In a multicenter cohort of more than 9000 primary shoulder arthroplasty procedures, the use of preoperative TXA was not associated with a decrease in the 5-year probability of revision for deep infection.
1197-18-8 Process route
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- 1197-17-7,1197-18-8,701-54-2
4-aminomethyl-cyclohexanecarboxylic acid
| Conditions | Yield |
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- 953817-12-4
C12H17NO5
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- 108-31-6
maleic anhydride
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- 1197-18-8
trans-4-aminomethyl-cyclohexyl-carboxylic acid
| Conditions | Yield |
|---|---|
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With hydrogenchloride; In water; for 1h; Kinetics;
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1197-18-8 Upstream products
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15177-68-1
trans-4-cyanocyclohexane-1-ylcarboxylic acid
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19145-95-0
methyl trans-4-cyanocyclohexane-1-carboxylate
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953817-12-4
C12H17NO5
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1129-35-7
4-cyanobenzoic acid methyl ester
1197-18-8 Downstream products
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23199-14-6
4-aminomethyl-cyclohexanecarboxylic acid methyl ester
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102196-03-2
methyl 3-
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927869-66-7
4-((2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-7-sulfonamido)methyl)cyclohexanecarboxylic acid
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1074-62-0
4-(aminomethyl)-cyclohexanemethanol
