6153-33-9

  • Product Name:Mebhydrolin napadisylate
  • Molecular Formula:2(C19H20N2).C10H8O6S2
  • Purity:99%
  • Molecular Weight:
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Product Details

Purity:99%

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6153-33-9 Name

Name

Mebhydroline napadisylate

Synonym

MEBHYDROLINE 1,5-NAPHTHALENEDISULFONATE SALT;MEBHYDROLINE NAPADISYLATE;MEBHYDROLIN NAPADISYLATE;DIAZOLINE;mebhydrolin napadisilate;9-Benzyl-N-Methyl-1,2,3,4-Tetrahydro-A-Carboline;MEBHYDROLINE 1,5-NAPHTHALENEDISULFONATE;incidal

 

6153-33-9 Biological Activity

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor

Research Areas >> Inflammation/Immunology

Target

Histamine H1-receptor[1]

 

6153-33-9 Chemical & Physical Properties

Melting point 

280°C (rough estimate)

Boiling point

424.2±38.0 °C at 760 mmHg

Density

1.8±0.1 g/cm3

Molecular Formula

C15H12BrI

Molecular Weight

399.064

Flash Point

210.4±26.8 °C

LogP

7.00

Exact Mass

397.916687

Vapour Pressure

0.0±1.0 mmHg at 25°C

Index of Refraction

1.667

storage temp. 

Inert atmosphere,Room Temperature

Pharmaceutical Intermediates Mebhydrolin napadisylate 6153-33-9 Export, Fast Delivery, High Purity

Mebhydrolin napadisylate, an oral antihistamine drug, is an antihistamine marketed in Australia as Fabahistin, and as an ingredient of Fabahistin Plus. Mebhydrolin (INN)  in medicine, is an antihistamine, which is one of the most widely used antihistamines and clemastine, a long-acting antihistamine. Pharmaceutical Intermediates Mebhydrolin napadisylate is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis. Mebhydrolin is in available in various countries, but not in the U.S.

InChI:InChI=1/2C19H20N2.C10H8O6S2/c2*1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15;11-17(12,13)9-5-1-3-7-8(9)4-2-6-10(7)18(14,15)16/h2*2-10H,11-14H2,1H3;1-6H,(H,11,12,13)(H,14,15,16)

Revelant articles of Mebhydroline napadisylate 6153-33-9

Repurposing of the antihistamine mebhydrolin napadisylate for treatment of Zika virus infection

Author links open overlay panelRui Zhou , Quanjie Li , Bo Yang, Yanni Quan, Yitong Liu, Meichen Liu, Yongxin Zhang, Guangzhi Shan, Zhourong Li, Jing Wang, Yanping Li, Shan Cen

, Bioorganic Chemistry Volume 128, November 2022, 106024

In this work, we screened several antihistamines for the ability to restrain ZIKV infection and identified mebhydrolin napadisylate (MHL) as an effective antiviral agent against ZIKV.

Densitometric determination of mebhydrolin napadisylate in tablets

L Wulandari, M Yuwono, G Indrayanto

JPC - Journal of Planar Chromatography - Modern TLC Print ISSN: 0933-4173

A simple and rapid high-performance thin-layer chromatography (HPTLC) densitometric method has been developed for the determination of mebhydrolin napadisylate in tablets. A simple and rapid high-performance thin-layer chromatography (HPTLC) densitometric method has been developed for the determination of mebhydrolin napadisylate in tablets.